RNA-seq in primary fibroblasts (Supplementary Fig. 2a–c) confirmed the RNA-seq results from human lung tissue (Fig. 1a), i.e., increased levels of MIRLET7D targets in IPF fibroblasts concomitant with fibrosis markers (Supplementary Fig. 2c, left). This evidence concerns the gene MIRLET7D and idiopathic pulmonary fibrosis.