For the four analyzed parameters (e.g., the percentage of middle ears that did not develop disease, the time to disease onset, the time to disease resolution, and the proportion of animals that developed OM), the results for the group that received serum against anti-PE mixed with anti-PilA (PE + PilA) were significantly different from those for the group that received AS04, and only trends were observed for the group that received PE-PilA. Here, HIVEP2-DT is linked to ocular melanoma.