To determine whether additional pathological hallmarks of synucleinopathies were recapitulated in our TgM83 astrocyte cultures, we examined the co-localization of aggregated and phosphorylated α-synuclein with ubiquitin and the ubiquitin-binding protein p62 (also known as sequestosome-1). The gene discussed is SQSTM1; the disease is synucleinopathy.