αS pathology distribution in M83+/− mice bilaterally injected with 2 μL of either human MSA patient brain lysate (10% w/v), or preformed fibrils comprised of A53T human αS (5 mg/ml) or WT human αS fibrils (5 mg/ml) as stained with antibodies 15-4E7 (A) and 33A-3F3 (B). This evidence concerns the gene PGAP6 and multiple system atrophy.