Global methylation profiles were investigated in BM HPSCs purified as CD34+ cells from 10 donors (t0) and 10 respective HM recipients [3 acute lymphoid leukemia (ALL), 6 acute myeloid leukemia (AML), and 1 Hodgkin lymphoma (HL)] in sequential time points [30 (t1), 60 (t2), 120 (t3), 180 (t4), and 365 (t5) days] after AHSCT. The gene discussed is CD34; the disease is acute myeloid leukemia.