PDE4B and schizophrenia: These circRNAs include CDR1as, which is highly expressed in the human brain [42], chr1:66378928|66384518 from PDE4B, which interacts with DISC1 to regulate cAMP signaling in schizophrenia [43], and chr2:160193973:160252345 from BAZ2B, which belongs to the bromodomain gene family associated with transcriptional activation [44].