BCL6 and diffuse large B-cell lymphoma: In our previous study about A-DLBCL [6], MYC/BCL2/BCL6 triple extra copies were found in 3 cases, and the overall survival is 5, 9, and 11 months, similar to the very aggressive disease course and poor prognosis of primary CNS A-DLBCL cases in this study, suggesting that in this specific morphology (anaplastic variant), MYC/BCL2/BCL6 copy number alterations may be an adverse prognostic factor, but more cases are needed to confirm this finding.