GH1 and pituitary gland adenoma: As a benign tumour derived from the anterior pituitary gland, some pituitary adenomas, like FPA, can induce endocrine disorders by the hypersecretion of hormone, such as adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), growth hormone (GH) and prolactin (PRL) [6].