Different studies have identified genes involved in uveal melanoma development, such as GNAQ (G protein subunit alpha q), GNA11 (G protein subunit alpha 11), CYSLTR2 (cysteinyl leukotriene receptor 2), PLCB4 (phospholipase C, β4), BAP1 (BRCA1-associated protein 1), SF3B1 (splicing factor 3B subunit 1), SRSF2 (serine and arginine rich splicing factor 2), EIF1AX (X-linked eukaryotic translation initiation factor 1A) and TERT (telomerase reverse transcriptase). This evidence concerns the gene GNA11 and uveal melanoma.