Of note, when the platelets were disaggregated from leukocytes with EDTA, leukocyte adhesion to TNFα-stimulated HUAEC was evidently diminished, but this parameter was markedly greater in the metabolic syndrome group than the control group and again monocytes mainly expressed CCR2 and CX3CR1 receptors (Figure 7D,F,H,J). Here, TNF is linked to metabolic syndrome.