Lysine-specific demethylase 1 (LSD1/KDM1A) is a histone demethylase that removes mono- and dimethyl-lysine 4 of histone H3 (H3K4me1/2) [16] and is overexpressed in various cancer types including breast, lung, and prostate cancer [17]. Here, KDM1A is linked to Familial prostate cancer.