IFNB1 and infection: qPCR analysis indicated that induction of antiviral genes including IFNB1, ISG56 and CXCL10 following infection with the DNA viruses HCMV, herpes simplex virus 1 (HSV-1), and vaccinia virus (VACV) was inhibited in HFF-UL42 as compared to empty vector-transduced control cells (HFF-Vec) (Fig 1C).