Consistently, mRNA levels of IFNB1, ISG56, CXCL10, and IL6 genes induced by HCMV-ΔUL42 were significantly higher than those induced by HCMV-WT at 6, 12, and 24 hr post-infection in HFFs, human primary monocyte-derived dendritic cells and macrophages (Fig 2C). The gene discussed is IFIT1; the disease is infection.