Furthermore, elevated levels of IL-1β were detected in supernatants from cultured human L. braziliensis cutaneous leishmaniasis lesion biopsies compared to healthy skin controls, and a greater percentage of myeloid cells, particularly granulocytes, from lesion biopsies were pro-IL-1β+ compared to peripheral blood mononuclear cells from those same patients [21]. The gene discussed is IL1B; the disease is cutaneous leishmaniasis.