These findings were recapitulated in KEAP1WT and KEAP1MUT NSCLC cell lines expressing NRF2T80K or following KEAP1 restoration, respectively (Figure 5H–K), with the exception of H322, which maintained CYS-SO32- production following KEAP1 restoration (Figure 5—figure supplement 3G). Here, KEAP1 is linked to non-small cell lung carcinoma.