A receptor closely related to VEGF is Neuropilin-1 (NRP-1), which has been associated with the progression of different types of cancer including breast cancer (6–10) and direct NRP-1 targeting via miR-376a suppressed the progression of breast cancer cells (11) Therefore, current research suggest that targeting NRP-1 might be a new strategy for cancer treatment (12). This evidence concerns the gene VEGFA and breast carcinoma.