While mycosis fungoides (MF) and Sézary syndrome (SS) are the most commonly recognized subtypes, other variants of CTCL were documented by the 2016 World Health Organization classification of primary cutaneous lymphomas (4) and include angioimmunoblastic T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, adult T-cell leukemia/lymphoma (ATLL), mature T-cell lymphoma not otherwise specified (NOS), cluster of differentiation 30 positive (CD30+) T-cell lymphoproliferative disorders of the skin and extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKL). The gene discussed is TNFRSF8; the disease is primary cutaneous T-cell non-Hodgkin lymphoma.