TF and cancer: TF is also the therapeutic oncotarget for cancer cells and cancer stem cells (CSC) [16] (Figure 2 and Figure 3) for fVII-targeted immunotherapy using coagulation active site-mutated fVII-IgG1 Fc immunoconjugate (called an ICON) (Figure 4) and fVII-targeted photodynamic therapy (fVII-tPDT) using fVII-conjugated photosensitizers) [15,16], as summarized below.