HIF1A and glottis carcinoma: Schrijvers et al. (2008) detected three hypoxia markers, HIF-1α, CAIX, and GLUT-1, in 91 tissue samples of T1/T2 glottic carcinoma by IHC and found no significant relationship between GLUT-1 and HIF-1α expression, and GLUT-1 overexpression was not a predictor of worse local control or prognosis [69].