MEF2A and schizophrenia: In a cohort study of high-risk family subjects, microsatellite linkage analysis and whole genome sequencing identified causative variants in the linkage region and reported a MEF-2A binding site that was located between two genes associated with schizophrenia; the locus 6q25-26 has been implicated in formal thought disorder via dysregulated MEF-2A signaling [169].