Others loci are associated with hematological disorders such as CEBPA, FOXP1, MECOM and RHOH which promotes Acute myeloid leukemia [41], diffuse large B-cell lymphoma [42], myeloproliferative neoplasm [43] and B-cell chronic lymphocytic leukemia [44] respectively. The gene discussed is RHOH; the disease is diffuse large B-cell lymphoma.