In the third study, Hessam et al. (87) enrolled HS and psoriasis patients as well as healthy controls analyzed the expression profile of RNA-induced silencing complex (98) components (specifically, transactivation-responsive RNAbinding protein-1 (TRBP1), TRBP2, protein activator (PACT) of the interferon-induced protein kinase R, Argonaute RISC Catalytic Component-1 (AGO1) and Component- 2 (AGO2), metadherin, and staphylococcal nuclease and Tudor domain-containing-1 (SND1)), also in this case using RT QPCR, in their inflamed tissues (skin biopsies). Here, AGO1 is linked to psoriasis.