Immunohistochemistry revealed that 71.43% (45/63), 50.79% (32/63), and 58.73% (37/63) of ovarian cancer tissues with BC response stained positively for SEMA4D, VEGF and PD-L1, which were significantly higher than the positive staining in the group of ovarian cancer tissues with BC non-response (71.43% vs. 49.18%, 50.79% vs. 31.15%, and 58.73% vs. 39.34%, p < 0.05, respectively; Table 2). The gene discussed is CD274; the disease is ovarian cancer.