Univariate regression analysis revealed that plasma DAO levels positively correlated with age (β = 3.1, P = 0.0003) and with HTN (β = 67.49, P = 0.0003), and negatively with eGFR (β = −2.06, P = 1.47 X 10−10) (Supplementary Table 2). This evidence concerns the gene DAO and hypertensive disorder.