Immunofluorescent staining of mouse cortical astrocytes cultures and ELISA analysis of culture medium samples showed that while basal expression of Bdnf in unstimulated cells is relatively low, stimulation of astrocytes with a drug used for the treatment of relapsing-remitting multiple sclerosis (MS) increased BDNF expression and secretion about two-folds (Reick et al., 2016). Here, BDNF is linked to relapsing-remitting multiple sclerosis.