In the same xenograft tumor model, another shRNA (short hairpin RNA) and aptamer A10-3 to PSMA conjugate also exhibited biological activity (65% inhibition of the PRKDC gene), but tumor regression occurred after two intratumoral injections only in combination with ionizing radiation (Ni et al., 2011) (Supplementary Table 1). Here, FOLH1 is linked to neoplasm.