There are other first-generation jakinibs in clinical trials for autoimmune diseases: Ruxolitinib (JAK1 and JAK2 inhibitor) for GVHD (NCT02913261), Psoriasis (NCT00617994), and Vitiligo (NCT02809976); Baricitinib (JAK1 and JAK2 inhibitor) for GVHD (NCT02759731) and Diabetic nephropathy (NCT01683409). Here, JAK2 is linked to graft versus host disease.