EZH2 and posterior cortical atrophy: EZH2 is overexpressed in castration‐resistant PCa, and RT can reduce EZH2 expression in PCa cells.42 Moreover, small molecule inhibitors of EZH2 can induce cell death in vitro and in vivo in advanced PCa.42 However, studies specifically investigating links between EZH2 expression and PCa recurrence following RT, or the potential for inhibitors of EZH2 to radiosensitize PCa cells, are lacking.