Our statistics found that after the treatment of statins in patients with hyperlipidemia related proteinuria there was no statistically significant effect on serum lipids, renal damage, and serum ANGPTL3 expression levels, which may be affected by the small sample size of the early collection, the detection method and the poor compliance in patients with hyperlipidemia related proteinuria. Here, ANGPTL3 is linked to hyperlipidemia.