Wide excision of the bilateral thyroid mass with bilateral lymph node dissection was done on April 25, 2017, and documented papillary carcinoma (solid variant, sized 5.3 cm with lymphovascular invasion, extensive extrathyroid extension to adjacent organs and tissues and perineural invasion, T4aN1bM1, stage 4c) with tumor invasion to bilateral recurrent laryngeal nerve but negative for BRAF V600E gene mutation (Additional file 1: Figure S2). This evidence concerns the gene BRAF and papillary carcinoma.