FOXD1 is highly expressed in the kidney and regulates the cellularity of the renal capsule, an important structure in normal kidney.19, 20 FOXD1 also exists in the brain and retina and is necessary for a normal retinal and optic chiasm development.21, 22 FOXD1 is also an oncogene as it promotes cell proliferation and chemotherapeutic drug resistance in breast cancer.23, 24 Moreover, FOXD1 silencing inhibits proliferation and migration in glioma cells.25 However, whether FOXD1‐AS1 is associated with glioma remains unknown. Here, PTGDR is linked to central nervous system cancer.