SPO11 and neoplasm: This work was extended to demonstrate that the oncogenic role of the D. melanogaster orthologue of SPO11 (Mei‐W68) for tumour formation could be suppressed, to some degree, by ionizing irradiation, suggesting that the function that Mei‐W68 mediates is DSB‐associated (although this remains to be fully determined as irradiation does activate a small cohort of additional genes which could potentially suppress the need for a non‐DSB‐forming function of Mei‐W68) (Rossi et al., 2017).