Using dual-color FISH, we analyzed 21 cases, including 13 cylindromas, 7 spiradenomas, and 1 cylindroma–spiradenoma hybrid tumor in addition to an adenoid cystic carcinoma case known to carry the MYB-NFIB fusion as a control. Here, NFIB is linked to adnexal spiradenoma/cylindroma of a sweat gland.