Available RNA sequencing data from a panel of HER2+ and triple-negative-enriched breast cancer cell lines [22] also showed a negative correlation between ERBB2 and ITGA3 expression (Fig. 4b), although no such clear correlation could be observed in larger and more diverse breast cancer cell line panel [32, 33], indicating that the regulation of α3β1 expression could be breast cancer cell type-dependent (Additional file 3: Figure S3b). This evidence concerns the gene ERBB2 and breast carcinoma.