ITGA3 and neoplasm: To investigate whether the differences in tumor volume between Itga3 KO and WT mice originated from different growth rates during the first weeks of tumor formation (i.e., in the early stages of oncogenesis), we determined the slopes of trend lines of average tumor size per mouse for both Itga3 KO and WT groups during the first 3 weeks after tumors were detected (Fig. 2d) and the last 3 weeks before individual mouse had to be sacrificed (Fig. 2e).