Low NKp30B/C ratios have been observed in response to higher transcription levels of isoform C, while a low NKp30A/C ratio was attributed to diminished isoform B expression; both of these findings suggest that differing ratios of the NKp30 isoforms may influence the outcome of GIST [32]. The gene discussed is NCR3; the disease is gastrointestinal stromal tumor.