CD4 and infection: As expected, the results showed that HIVgp(T)-VLPs can efficiently infect and produced high Gluc activity in CD4+ C8166 T cells, while HIVgp(M)-VLPs and HIVgp(M)/EboGP-VLPs infection did not produce significant levels of Gluc activity as compared to negative control (Gag-VLP) (Fig 1C).