Moreover, the binding of P‐selectin to its main receptor, P‐selectin glycoprotein ligand‐1, triggers thrombus growth and fibrin formation and thereby leads to a hypercoagulable state.19 Prior studies revealed an association of sP‐selectin with VTE and ATE in populations without cancer.26, 27, 28, 29, 30 Elevated sP‐selectin levels have also been identified to predict cancer‐associated VTE.31 The role of d‐dimer and sP‐selectin levels for prediction of ATE in patients with cancer is currently unknown. The gene discussed is SELP; the disease is cancer.