BDNF and schizophrenia: Hence, the aim of the present study was two-fold—(a) to assess and compare BDNF plasma level changes after 26-week supplementation with concentrated fish oil rich in n−3 PUFA or with a placebo (olive oil) and (b) to determine whether BDNF plasma level changes are related to improvements in psychopathology, disease severity, and patient functioning in those diagnosed with first episode of schizophrenia.