BDNF and schizophrenia: Pedrini et al. (2011) have also reported serum BDNF levels to be significantly correlated with clozapine daily dose, but not the typical antipsychotic daily dose; however, other longitudinal studies have not found any increase in serum BDNF levels in patients with schizophrenia after antipsychotic treatment (Pirildar et al. 2004; Rizos et al. 2010; Yoshimura et al. 2010; Kudlek Mikulic et al. 2017).