GPT and steatosis: The long-lasting MCDD challenge (7 weeks) aggravated the liver complications with severe steatosis (from 50 ± 8% at 2 w to 81 ± 3% at 7 w, p = 0.0201), inflammation (from 9 ± 3 foci/10 fields at 2 w to 77 ± 7% at 7 w, p = 0.0024) and liver injury (ALT activity from 51 ± 7 U/L at 2 w to 282 ± 42 U/L at 7 w, p = 0.0024) (Supplementary Fig. 2).