We screened HCC cell lines previously classified based on their response to TGFβ signaling, as epithelial-like cells with an early TGFβ target gene signature (Huh7, PLC/PRF5, Hep3b, HepG2) and as mesenchymal-like cells with a late signature (SNU398, SNU423, HLF, SNU449)21. Here, TGFB1 is linked to hepatocellular carcinoma.