IRF4 and aneurysmal bone cyst: Additional proposed methods following the establishment of the Hans algorithm included the Muris algorithm, which assesses BCL2, CD10, and IRF4/MUM1 expression35, identification of LMO2 as a prognostic marker by Natkunam et al.36, and Nyman et al.37 defining the ABC subtype as having positive expression of either IRF4/MUM1 or FOXP1.