Given the prior use of HLA-DPB1-restricted MAGE-A3-specific CD4+ T cells, we analyzed mRNA expression of HLA-DPB1 and found that expression was significantly higher in UPS/MFS compare to leiomyosarcoma (p < 0.01) and synovial sarcoma (p < 0.001). This evidence concerns the gene MAGEA3 and undifferentiated pleomorphic sarcoma.