In a KRASG12D-driven mouse model of lung cancer [56], tumor cells expressing the EMT transcription factor Snail secreted a soluble mediator, which increased Gr1+ neutrophil infiltration and secretion of the chemokine C-X-C motif chemokine ligand (CXCL) 2 by the neutrophils themselves. The gene discussed is SNAI1; the disease is neoplasm.