INS and type 2 diabetes mellitus: A study examining the effect of grilled cladode (500 g) in matched T2DM (n = 14) and healthy (n = 14) participants reported significant reductions in GLU (1 h: 1.19 ± 0.21 mM, p < 0.005; 2 h: 1.57 ± 0.28 mM, p < 0.005; 3 h: 2.26 ± 0.25 mM, p < 0.001) and INS (p <0.01; 1 h: 12.3 ± 15.9; 2 h: 3 h: 36.9 ± 10.8 pM; 56.4 ± 10.8 pM) in T2DM but not in a healthy group [43].