MMP2 and exstrophy-epispadias complex: Next, in order to further investigate whether the gradual increase in HMGA1 expression along with tumor staging and its impact on EEC patients’ survival could be related with a gain in tumor invasiveness, correlations analyses between HMGA1 and HMGA2 expression levels and those of the metalloproteinases MMP2 and MMP9 were performed using TCGA EEC expression data.