Romero-Pérez and colleagues reported that HMGA2 mRNA and protein overexpression participates in nonendometrioid carcinomas and endometrial carcinosarcomas development but not in that of EEC, suggesting its levels as a potential marker to distinguish between endometrioid and nonendometrioid endometrial tumors [39]. This evidence concerns the gene HMGA2 and exstrophy-epispadias complex.