In line with these observations, Hillion and colleagues recently evaluated HMGA1 expression in three different histopathological types of uterine tumors (regardless of FIGO staging classification and histological grade within each of the groups investigated) and showed that HMGA1 is more expressed in high-grade uterine tumors, such as endometrial serous carcinoma and uterine carcinosarcoma, than in less aggressive ones, such as EEC, suggesting an increase in HMGA1 expression along with uterine tumor aggressiveness [22]. Here, HMGA1 is linked to exstrophy-epispadias complex.