A mutation on the methyltransferase NADH:Ubiquinone Oxidoreductase Complex Assembly Factor 7 (NDUFAF7), which is an assembly factor of complex I, has been found in association with the reduction of intracellular ROS and ATP levels and with the reduction of Complex I activity, and it has also been correlated with pathologic myopia [81]. This evidence concerns the gene NDUFAF7 and pathological myopia.