The EOC cells, for instance, are able to polarize macrophages toward a tumor-associated phenotype [38] by secreting several factors, such as the colony-stimulating factor 1 (CSF-1), which acts as both a chemoattractant and a mitogen for circulating monocytes via tyrosine kinase receptor CSF1-R binding [39]. This evidence concerns the gene CSF1 and neoplasm.