Furthermore, to investigate the specific biomarkers of LC related cerebral hemorrhage, the Index of LC related cerebral hemorrhage was calculated as follows: firstly, the products of PT, CEA, and CA199 from both LCRCH group (35,786.35 ± 32,323.90) and LC group (2424.96 ± 2263.57) were calculated. The gene discussed is CEACAM5; the disease is laryngotracheoesophageal cleft.