DMD and Duchenne muscular dystrophy: During development, structure and distribution of bladder smooth muscle and urothelial cells undergo changes to permit functional adaptation.11 Morphological changes could be accompanied by alterations in dystrophin expression.12 In addition, changes occurring in the cellular localization of other DGC proteins in DMD are a secondary consequence of the absence of dystrophin.7 Having considered these morphological changes and the occurrence of age‐related LUTS in DMD, we sought to evaluate dystrophin isoform expression during postnatal development of the healthy rat urinary bladder.