Indeed KIAA0753, which falls within our 25% cFDR list of cilium genes, was shown to interact with OFD1 and FOR20 at pericentriolar satellites and centrosomes, and gives rise to oral-facial-digital syndrome [47], a phenotype associated with disruption in the ciliary transition zone and the basal body. Here, OFD1 is linked to orofaciodigital syndrome.