Immature plasma cells with low CXCR4 content have been observed in GBS patients 20; CXCR4 is also a gene that exerts significant roles in many immune processes, such as myelopoiesis, haematopoiesis and B‐cell lymphopoiesis.21, 22 STAT1 can regulate multiple immune system reactions, such as cell death and anti‐microbial activities, as biological and medical studies have rapidly developed, the role of STAT1 in tumorigenesis has emerged.23 Researchers have demonstrated that JAK1 (Janus‐associated kinase 1) can serve as an inhibitor in the treatment of immune disorders. This evidence concerns the gene JAK1 and immune system disorder.